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My dog has hives after vaccines-allergic reaction

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Allergic reactions to vaccines in dogs are uncommon but can happen. Most dogs tolerate vaccines well, but some may develop mild or more serious reactions. Here’s a breakdown:

 

(Common) Reactions

These usually appear within a few hours and resolve on their own:

  • Lethargy (tiredness)

  • Mild fever

  • Soreness or swelling at the injection site

  • Reduced appetite

  • Temporary lumps under the skin (vet may recommend benedryl)

 

Moderate Reactions

May need veterinary attention if persistent:

  • Vomiting

  • Diarrhea

  • Facial swelling (lips, eyelids, muzzle)

  • Hives or itchy bumps on the skin

 

Severe (Rare, Emergency) Reactions – Anaphylaxis

These typically happen within minutes to an hour after vaccination and require immediate veterinary care:

  • Collapse or fainting

  • Difficulty breathing (wheezing, gasping)

  • Pale gums

  • Severe swelling of face/throat

  • Seizures

 

Risk Factors

  • Small-breed dogs may be slightly more prone to reactions.

  • Reactions are more likely when multiple vaccines are given at once.

  • Dogs with a history of vaccine sensitivity.

 

What to Do if Your Dog Has a Reaction

  • Mild: Monitor at home, contact your vet if symptoms worsen or don’t resolve in 24 hours.

  • Moderate: Call your vet promptly for advice—may need antihistamines or anti-inflammatory medication.

  • Severe: Treat as an emergency—go to the vet or emergency clinic immediately.

 

Prevention & Management

  • Tell your vet if your dog has had a reaction before—pre-treatment with antihistamines or steroids may be recommended.

  • Spacing out vaccines instead of giving several at once can reduce risk.

  • Some dogs with severe past reactions may be exempt from certain vaccines, depending on laws and health risks.

 

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